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In the case of NF1, no clear links between genotype and phenotype have been found, and the severity and the specific nature of the symptoms may vary widely among family members with the disorder.

Because of the tumor generating nature of the disorder and its involvement of the nervous system and also because of early onset macrocephaly in the pediatric population, there is often an increased chance of development of epilepsy in those affected.

Neurofibromatosis also increases the risk of leukemia particularly in children; Children with NF-1 have 200 to 500 times the normal risk of developing leukemia compared to the general population.

The tumors may cause bumps under the skin, colored spots, skeletal problems, pressure on spinal nerve roots, and other neurological problems.

Neurofibromatosis is an autosomal dominant disorder, which means only one copy of the affected gene is needed for the disorder to develop.

If anyone sees a case like this in his home environment, I hope to help by submitting photos of patients with a short history I hope this paper, which is part of my essay book entitled “KNOW AND OVERCOMING MEDICAL ANOMALY” SHOULD, LIKE THIS CASE DOES NOT NEED TO HAPPEN, IF PEOPLE KNOW PERKEMABNAGN DISEASE (PAOGENESIS) MEDICAL AND EFFORT THAT CAN BE EXECUTED.

I hope this article can menambas insightful readers, and prevent the disorder becomes severe anomalies as reported by colleagues from the United States. June 2011 Dr Iwan suwandy, MHA Neurofibromatosis (commonly abbreviated NF; neurofibromatosis type 1 is also known as von Recklinghausen disease) is a genetically-inherited disorder in which the nerve tissue grows tumors (i.e., neurofibromas) that may be benign or may cause serious damage by compressing nerves and other tissues.

Saya harap tulisan ini dapat menamba H wawasan pembaca,sekaligus mencegah kelainan menjadi anomali yang sangat parah seperti yang dilaporkan oleh sejawat dari Amerika Serikat. Juni 2011 Dr Iwan suwandy, MHA ENGLISH VERSION: Neurofibromatosis is a disorder (anomaly or Osis) Medical from the growing tissue (fibro) nerve (neuro) new (neoplasms or tumors) are abnormal, though it may be benign, but malignant demaged caused the body and face posture ‘s demage .